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    Antimalarialpyronaridine resistance may be associated with elevated MDR-1 gene expression profiles but not point mutation in Plasmodium bergheiANKA isolates 

    Kimani, Shadrack Kanyonji; Shume, Jacob Manyiwa (African Journal of Biochemistry Research, 2020-08)
    Theselectionofresistance is inevitable whenever chemotherapy isnecessaryforpathogencontrol. Notably, Plasmodiumfalciparum has developed multifacetedmeans to overcomethetoxicityof nearly allantimalarial medicines. To ...
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    Antimalarial pyronaridine resistance may be associated with elevated MDR-1 gene expression profiles but not point mutation in Plasmodium berghei ANKA isolates 

    Kimani, Shadrack Kanyonji; Shume, Jacob Manyiwa (African Journal of Biochemistry Research, 2020-08)
    The selection of resistance is inevitable whenever chemotherapy is necessary for pathogen control. Notably, Plasmodium falciparum has developed multifaceted means to overcome the toxicity of nearly all antimalarial medicines. ...

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    AuthorKimani, Shadrack Kanyonji (2)Shume, Jacob Manyiwa (2)Subjectexpression (2)malaria (2)MDR-1 gene (2)
    Pyramax® (2)
    Pyronaridine (2)Quinolines (2)resistance (2)... View MoreDate Issued2020 (2)Has File(s)Yes (2)

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