Browsing by Author "Okoyo, Collins"

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    Current Status of Soil-Transmitted Helminths among School Children in Kakamega County, Western Kenya Prevalence and Intensity of Intestinal Parasites in School age Children in Thika District, Kenya
    (Hindawi Publishing Corporation, 2016-02-17) Ngonjo, Teresia; Okoyo, Collins; Andove, Julius; Simiyu, Elses; Lelo, Agola Eric; Kabiru, Ephantus; Kihara, Jimmy; Mwandawiro, Charles
    Background. School age children are at high risk of soil-transmitted helminth (STH) worldwide. In Kenya, STH infections in children remain high despite the periodic administration of anthelmintic drugs. Our study assessed the prevalence and intensity of STH in primary school-aged children in Kakamega County, western Kenya. Methodology. We carried out a cross-sectional study on a population of 731 children attending 7 primary schools in March 2014. Children aged 4–16 years were examined for STH by the quantitative Kato-Katz technique. Infection intensities were expressed as eggs per gram (epg) of faeces. Findings. Among 731 school children examined for STH, 44.05% were infected. Highest prevalence of STH was in Shitaho primary school where 107 participants were examined and 62.6% were infected with mean intensity of 11667 epg. Iyenga had the least prevalence where 101 participants were examined and 26.7% were infected with mean intensity of 11772 epg. A. lumbricoides was the most prevalent STH species with 43.5% infected, while hookworm infections were low with 1.8% infected. Conclusion. Prevalence of STHs infections in Kakamega County remains high. We recommend guidelines and other control strategies to be scaled up to break transmission cycles.
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    Effectiveness of albendazole on soil transmitted nematodes among school children-: a case of Kakamega County, Kenya
    (2019-03-25) Ngonjo, T.W.; Okoyo, Collins; Simiyu, Elses; Kihara, Jimmy; Lelo, Agola Eric; Kabiru, Ephantus; Mwandawiro, Charles
    Background: Recent assessment by WHO on Soil Transmitted Nematodes (STN) point that their morbidity is still high in people mainly in children. A. lumbricoides globally infects 1.2 billion people and T. trichiura 795 million worldwide. Infections with Ancylostoma duodenale and Necator americanus 740 million leading to 135,000 deaths per year. It became necessary to find out the effectiveness of Albendazole on soil transmitted Nematodes among school children- a case of kakamega county, kenya. Methodology: Study respondents were selected fom public primary school children in Kakamega County. A total of 731 and 665 (pre & post) children in 7 primary schools in three sub counties of Kakamega County were recruited in the study. Pre-treatment survey was done in March, 2014 and follow up in September 2014. Fecal samples were examined for the presence of STN . 14 days after treatment using Kato- Katz method. The total number of eggs were expressed as eggs/gm of feaces (epg). Pretreatment prevalence was 43.5% for Ascaris lumbricoides, 1.8% for hookworm and 0.9% for Trichuris trichiura. Results: Mean intensity of hookworm, A. lumbricoides and T. trichiura infections in the pre-and post-surveys were reduced by 1.2%, 98.4% and 100% respectively. Prevalence decreased to 2.3% for Ascaris lumbricoides and 0 % for T. trichiura. Post treatment prevalence of A. lumbricoides and T. trichiura infections were significantly reduced by 94.8% and 100% respectively. A slight increase in hookworm prevalence was observed. However, this increase was not significant (p=0.993). Conclusion: The therapeutic efficacy of Albendazole indicated a good reduction in parasite burden. Albendazole satisfactorily reduced STN infection while for hookworm there was a non-significant increase in prevalence.
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    Effectiveness Of Albendazole On Soil Transmitted Nematodes Among School ChildrenA Case Of Kakamega County, Kenya
    (African Journal of Health Sciences, 2019) Ngonjo, T.W.; Okoyo, Collins; Simiyu, Elses; Kihara, Jimmy; Lelo, Agola Eric; Kabiru, Ephantus; Mwandawiro, Charles
    Recent assessment by WHO on Soil Transmitted Nematodes (STN) point that their morbidity is still high in people mainly in children. A. lumbricoidesglobally infects 1.2 billion people and T. trichiura795 million worldwide. Infections withAncylostoma duodenaleand Necator americanus 740 million leading to 135,000 deaths per year. It became necessary to find out the effectiveness of Albendazoleonsoil transmittedNematodesamong school children- a case of kakamega county, kenya.METHODOLOGYStudy respondents were selected fom public primary school children in Kakamega County. A total of 731 and 665 (pre & post) children in 7 primary schools in three sub counties of Kakamega County were recruited in the study. Pre-treatment survey was done in March, 2014 and follow up in September 2014. Fecal samples were examined for the presence of STN . 14 days after treatment using Kato- Katz method.The total number of eggs were expressed as eggs/gm of feaces (epg). Pretreatment prevalence was 43.5% for Ascaris lumbricoides, 1.8% for hookworm and 0.9% for Trichuris trichiura. R ESU LTSMean intensity of hookworm, A. lumbricoides and T. trichiura infections in the pre-and post-surveys were reduced by 1.2%, 98.4% and 100% respectively. Prevalence decreased to 2.3% for Ascaris lumbricoides and 0 % for T. trichiura. Post treatment prevalence of A. lumbricoides and T. trichiura infections were significantly reduced by 94.8% and 100% respectively. A slight increase in hookworm prevalence was observed. However, this increase was not significant (p=0.993). CONCLUSIONThe therapeutic efficacy of Albendazole indicated a good reduction in parasite burden. Albendazole satisfactorily reduced STN infection while for hookworm there was a non-significant increase in prevalence. Key words: Cure rate, egg reduction rate, albendazole, Kenya